MISTMIST| Species | PPIs | Genes covered by PPIs | avg # of PPI partners | all PPIs (include interologs) | Genes covered by all PPIs | avg # of partners, all PPIs | PPIs of high/moderate rank | Genes covered by high/moderate PPIs | avg # of partners for PPIs of high/moderate rank |
|---|---|---|---|---|---|---|---|---|---|
| FlyBi | 33635 | 6445 | 5.2 | 33635.0 | 6445.0 | 5.2 | 33635 | 6445 | 5.2 |
| S. pombe | 29049 | 3582 | 8.1 | 453719 | 4593 | 98.8 | 103768 | 3732 | 27.8 |
| S. cerevisiae | 325749 | 6101 | 53.4 | 603819 | 6102 | 99.0 | 170302 | 5497 | 31.0 |
| C. elegans | 84407 | 8740 | 9.7 | 887453 | 10973 | 80.9 | 176203 | 7647 | 23.0 |
| D. melanogaster | 268683 | 11012 | 24.4 | 1121475 | 11872 | 94.5 | 260483 | 9316 | 28.0 |
| D. rerio | 799 | 383 | 2.1 | 1578121 | 16736 | 94.3 | 181918 | 11235 | 16.2 |
| X. laevis | 4017 | 1343 | 3.0 | 1465821 | 16759 | 87.5 | 128415 | 8706 | 14.8 |
| X. tropicalis | 19 | 11 | 1.7 | 1100669 | 13220 | 83.3 | 119630 | 8575 | 14.0 |
| H. sapiens | 1007349 | 19175 | 52.5 | 1628439 | 19432 | 83.8 | 583227 | 16925 | 34.5 |
| M. musculus | 116845 | 10774 | 10.8 | 1582923 | 17889 | 88.5 | 170352 | 10992 | 15.5 |
| R. norvegicus | 22403 | 4535 | 4.9 | 1451149 | 17309 | 83.8 | 144953 | 10854 | 13.4 |
| Species | GIs | Genes covered by GIs | avg # of GI partners | all GIs (includes interologs) | Genes covered by all GIs | Genes covered by all GIs | GIs of high/moderate rank | Genes covered by high/moderate GIs | avg # of partners for GIs of high/moderate rank | |
|---|---|---|---|---|---|---|---|---|---|---|
| S. pombe | 103986 | 3540 | 29.4 | 634768 | 4649 | 136.5 | 31895 | 2877 | 11.1 | |
| S. cerevisiae | 883611 | 5840 | 151.3 | 958625 | 5846 | 164.0 | 135224 | 4957 | 27.3 | |
| C. elegans | 16000 | 3174 | 5.0 | 431937 | 6260 | 69.0 | 21176 | 2491 | 8.5 | |
| D. melanogaster | 27742 | 4206 | 6.6 | 499435 | 7317 | 68.3 | 33305 | 3558 | 9.4 | |
| D. rerio | 129 | 65 | 2.0 | 635188 | 8411 | 75.5 | 32168 | 3174 | 10.1 | |
| X. laevis | 14 | 10 | 1.4 | 597517 | 9331 | 64.0 | 19662 | 2758 | 7.1 | |
| X. tropicalis | NA | NA | NA | 370474 | 6617 | 56 | 15540 | 2258 | 6.9 | |
| H. sapiens | 17423 | 3379 | 5.2 | 622432 | 8271 | 75.3 | 29096 | 2970 | 9.8 | |
| M. musculus | 655 | 329 | 2.0 | 633941 | 8181 | 77.5 | 30420 | 3108 | 9.8 | |
| R. norvegicus | 34 | 27 | 1.3 | 501482 | 7863 | 63.8 | 23015 | 2776 | 8.3 |
| Source | Version or date of dowload | Interactions included in MIST (vs3) | Interactions included in MIST (vs4) | Interactions included in MIST (vs5) | Increase | Non-overlapping interactions (vs3) | Non-overlapping interactions (vs4) | Non-overlapping interactions (vs5) | Interaction types | Species for MIST |
|---|---|---|---|---|---|---|---|---|---|---|
| DIP | dip20170205 | 106,660 | 106,660 | 106,660 | 0.00% | 6,517 | 921 | 911 | PPI | 10 |
| DroID (including DPiM) | v2018_8 | 247,816 | 280,617 | 280,617 | 0.00% | 129,219 | 128,632 | 128,609 | PPI,GI | 1 |
| BioGrid | vs3.5.181 | 1,827,231 | 2,114,921 | 2,254,088 | 6.60% | 1,105,722 | 1,198,044 | 1,310,523 | PPI,GI | 9 |
| IntAct (including MINT) | 2/26/2020 | 634,547 | 764,334 | 920,762 | 20.50% | 16,381 | 56,505 | 87,067 | PPI,GI | 10 |
| FlyBase | FB2020_1 | 64,007 | 78,661 | 84,066 | 6.90% | 21,192 | 2,881 | 4,940 | PPI,GI | 1 |
| HPRD | Release9 | 76,233 | 76,233 | 76,233 | 0.00% | 23,363 | 22,743 | 22,328 | PPI | 2 |
| PomBase | 6/22/2017 | 5,290 | 5,290 | 5,290 | 0.00% | 3,624 | 3,495 | 3,487 | PPI | 1 |
| mentha | 2/24/2020 | 1,020,351 | 1,202,463 | 1,204,907 | 0.20% | 9,454 | 12,108 | 10,540 | PPI | 9 |
| HumanMAPK | manuscript table (2010) | 4,530 | 4,530 | 4,530 | 0.00% | 2,941 | 2,911 | 2,897 | PPI | 1 |
| WormBase | WS276 | NA | 53,078 | 61,866 | 16.60% | NA | 29,999 | 38,280 | PPI,GI | 1 |
| MIST (without interologs) | vs5 | 2,376,341 | 2,737,466 | 2,945,200 | 7.60% | NA | NA | NA | PPI,GI | 10 |
| MIST (including interologs) | vs5 | 13,573,897 | 16,441,356 | 17,801,051 | 8.30% | NA | NA | NA | PPI,GI | 10 |