InsulinNet provides access to a comprehensive Drosophila InR/PI3K/Akt network generated at Perrimon Lab (Harvard Medical School) by combining biochemical, genetic and computational approaches.
The user interface was built using integrated data from protein-protein interaction (PPI), RNA interference (RNAi), and phosphoproteomics networks, together with cytoscape.js. The JSON files for these networks have a predefined layout and style, including predefined node color, shape, and edge colors. These were exported from Cytoscape and provided as an input to a Cytoscape javascript library in order to create the platform.
TopThe platform provides access to InsulinNet-PPI (PPI network generated using Tandem Affinity Purification followed by Mass Spectrometry), integrated InsulinNet (PPI network integrated with RNAi and phosphoproteomic data) and a protein complex view of InsulinNet. You can query the proteins in this network with the help of search box.
Perrimon lab Department of Genetics Harvard Medical School New Research Building, Room 336 77 Avenue Louis Pasteur Boston, MA 02115 Fax: (617)432-7688 Email: perrimon@receptor.med.harvard.eduTop